Type IV OI (OI Type IV) | Brittle Bone Disorders

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An NIH-Funded Rare Diseases Clinical Research Network Consortium

Sometimes referred to as the "moderate" form of osteogenesis imperfecta. It is in between Type I and Type III in severity.

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The Brittle Bone Disorders Consortium (BBDC) is part of the Rare Diseases Clinical Research Network (RDCRN), which is funded by the National Institutes of Health (NIH) and led by the National Center for Advancing Translational Sciences (NCATS) through its Division of Rare Diseases Research Innovation (DRDRI). BBDC is funded under grant number U54AR068069 as a collaboration between NCATS, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Dental and Craniofacial Research (NIDCR), the National Human Genome Research Institute (NHGRI), the Office of Research on Women’s Health (ORWH), and the NIH Office of the Director (OD). This website is hosted by the network’s Data Management and Coordinating Center at Cincinnati Children’s Hospital Medical Center, which is funded by NCATS and the National Institute of Neurological Disorders and Stroke (NINDS) under grant number TR002818. The content of this website is solely the responsibility of the BBDC administrative coordinating center at Baylor College of Medicine and does not necessarily represent the official views of the NIH.

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